Partners

Janelia / HHMIETH ZurichSeeed StudioUniversity of HelsinkiSorbonneEPFLLichtwerkstattMax Delbrück Center Helmholtz InstituteAutodeskJanelia / HHMIETH ZurichSeeed StudioUniversity of HelsinkiSorbonneEPFLLichtwerkstattMax Delbrück Center Helmholtz InstituteAutodesk

One cube. Infinite microscopes.

Every openUC2 system is built from the same standardized building block: the UC2 cube. Each cube holds one optical component — a lens, mirror, LED, camera, or filter. Arrange them on a grid, and you have a microscope.

From optical principle to working instrument

The UC2 cube is a 50x50 mm standardized interface. Each cube holds exactly one optical element — a lens, a mirror, a beamsplitter, an LED, or a camera. Cubes connect magnetically on a baseplate grid, creating any optical path you can imagine.

This is the same principle at every scale:

In the classroom: Students snap cubes together to build a simple microscope and see how lenses form images.

In the lab: A PhD student adds a dichroic cube and a laser cube to build a fluorescence path, tests it, and iterates.

In production: The FRAME microscope houses cubes inside a rigid motorized stage — same optics, industrial-grade stability.

Try the Configurator

Cubify your optical design

Take any optical setup — a fluorescence microscope, a light-sheet system, a Michelson interferometer — and break it into standardized cube modules. Each cube maps to one component in your beam path.

This isn't just a teaching trick. It's a design methodology that makes optical prototyping as fast as rearranging blocks. Change your dichroic? Swap one cube. Add a second camera? Add one cube. Move from brightfield to phase contrast? Rearrange the grid.

Every cube-based prototype has a digital twin. Validate optically with ray tracing before building. Scale to CNC-machined production parts without redesign.

UC2 Ecosystem Diagram

Three paths, one platform

Whether you're teaching, researching, or deploying — the cube system grows with you.

FRAME microscope with motorized stage and fluorescence cubes
Professional & Industry

FRAME — Automated Microscope

A fully motorized XYZ scanning microscope built on UC2 cube architecture. Sub-micrometer precision, multi-channel fluorescence, browser-based control, REST API, and open-source software. Swap optical modules without realignment.

Who it's for: Research labs, core facilities, diagnostics R&D, biotech companies.

Contact for quote
Explore FRAME
Makers and researchers prototyping with the open platform
Makers & Research

Open Platform

The full open-source ecosystem: 3D-printable cube designs, electronics schematics, firmware (ESP32), and ImSwitch software. Build your own microscope from scratch, customize every component, and share your designs with the community.

Who it's for: PhD students, optics researchers, hardware startups, biohackers.

Discovery Lineup: CoreBox, Electronics Kit, Infinity Upgrade, QBox
Education

Discovery Line

Modular educational kits for teaching optics, microscopy, and imaging. Start with the CoreBox (analog optics), add electronics, upgrade to infinity-corrected systems, or explore quantum optics with the QBox.

Who it's for: Schools, universities, maker spaces, workshops, science outreach.

Explore Discovery

Funded by

Supported by leading European research funding programs.

Thüringer Aufbaubank Logo
Thüringer Aufbaubank (TAB)
European Union Logo
European Union and the local EFRE Structural Fund in Thuringia
BMFRT Logo
Bundesministerium für Forschung, Technologie und Raumfahrt

Not sure where to start?

Tell us what you want to image and we'll help you find the right configuration.